Monday, April 8, 2024

What Time Of The Day Is Best To Take Probiotics

Why Does The Align Probiotic Supplement Come In The 84 Count

Best Time to Take Probiotics & Prebiotics

While many over the counter products use a rounded 30-day supply, the Align probiotic is sold in this 84 count to give three sets of 28 capsules, as 28 days is an exact four week supply. Taking a single supplement each day means buyers enjoy exactly 12 full weeks of Align digestive care in each package. This also makes it likely that shoppers get the best price for Align probiotic through the bulk purchase.

It Can Depend On The Strain

Finally, its important to note that not all probiotic strains and formulas are alike.

For example, lactobacillus is a common probiotic strain. It relies on glucose to survive in an acidic environment like our stomachs. For that reason, it may pair best alongside sugar and carbohydrates.

However, different probiotic strains, and combinations of strains, may perform differently.

Mistake #: You Stop Taking Probiotics When You Take Antibiotics

One of the biggest misconceptions is that you should wait until your antibiotics are finished before you take probiotics, says registered dietitian Desiree Nielsen, author of Un-Junk Your Diet: How to Shop, Cook and Eat to Fight Inflammation and Feel Better, Forever. People think that antibiotics will kill probiotics, which is true, but probiotics can ease the side effects of antibiotics . The key to survival is when you take probiotics: wait two hours after your antibiotic dose so the antibiotic can move through your system and give probiotics a fighting chance. In addition, continue the probiotics for a time after your antibiotics are finished to ensure that their effects are out of your system.

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What To Look For

Prebiotics can be consumed in foods or in supplement form. Since prebiotics are non-digestible fibers they are found in many plant-foods that provide good nutrition. So when you increase your intake of prebiotic foods you gain health benefits from the other nutrition that they provide.

These prebiotic foods include many items that youâd find in your local market.

  • Asparagus

Oligosaccharides are the best-known prebiotics.

If you choose to buy a supplement, the National Institutes of Health recommends that you look for a Supplement Facts label on the product that you buy. This label will contain vital information including the amount of fiber per serving, and other added ingredients like fillers, binders, and flavorings.

Lastly, the organization suggests that you look for a product that contains a seal of approval from a third party organization that provides quality testing. These organizations include U.S. Pharmacopeia,, and NSF International. A seal of approval from one of these organizations does not guarantee the productâs safety or effectiveness but it does provide assurance that the product was properly manufactured, contains the ingredients listed on the label, and does not contain harmful levels of contaminants.

The Health Benefits Of Probiotics

What Is the Best (and Worst) Time to Take Probiotics?

Probiotics directly improve the enormous and complex community of bacteria in your gut, also known as your gut flora.

Gut flora is sometimes described as the forgotten organ. The trillions of bacteria in your gut actually play a vital role in the structure and function of the immune system.

Your gut flora even performs metabolic activities that resemble those of an organ. Despite this, the importance of optimizing gut flora health is not nearly as well understood as heart or skin health.

By replenishing and protecting gut flora, probiotics offer many benefits to the body:

  • Prevent diarrhea or constipation
  • Reduce symptoms of digestive disorders like ulcerative colitis, bloating, and IBS
  • Strengthen immune system by promoting natural antibodies and inhibiting harmful bacteria
  • Support weight loss and weight management goals

Keep in mind that not all probiotics are created equal. Its important to use a high-quality probiotic and take it at the right time of day in order to maximize its efficiency.

Also Check: Probiotic That Helps You Sleep

Taking Prebiotics For Weight Loss

Both human and animal research suggests of the importance of prebiotics and certain probiotic strains on the physical, biochemical, and metabolic parameters of weight control. Inulin-FOS, in particular, benefits weight loss by:

  • Absorbing water in the gut to satiate hunger
  • Mitigating calorie content of any food item
  • Reducing triglycerides
  • Promoting ghrelin for better appetite control
  • Slowing food transit time in gut to flatten blood sugar spikes

As a soluble fiber, inulin-FOS provides the well-known soluble fiber benefits for gut health, regular movements, and appetite control. All in all, inulin-FOS is a great supplement to take to improve your relationship to your diet.

How To Supplement With Probiotic

If you are seeking a probiotic supplement, you may find the selection process overwhelming. Two probiotic formulations that may work well for you are a probiotic blend or a yeast probiotic. A probiotic blend combines a few of the most studied strains of bacteria to confer great health benefits in one capsule. A yeast probiotic contains a single yeast strain that may provide recently researched benefits for your gut. If you are unsure about which probiotic is best for you, a health professional can help you make a decision. Choosing a probiotic from a reputable source with transparent labeling is always important.

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Should You Take Probiotics With Digestive Enzymes

Probiotic supplements that produce digestive enzymes can be taken with food. For example, our P3-OM prebiotics and probiotics supplements produce protein-digesting enzymes to help break down the proteins you eat. So, P3-OM can help optimize your digestion when taken with food.

Supplementation with probiotics and enzymes helps improve nutrient availability in the gut. The digestive enzyme supports the breakdown of food molecules, while at the same time, probiotics positively contribute to the gut microbial environment. Since both work in synergy, you can take probiotics that produce digestive enzymes or take them along with a digestive enzyme supplement like MassZymes.

When Should I Take Probiotics

When is the Best Time to Take Probiotics

The ideal time to take probiotics is right before bed because “the gut is pretty inactive at night. If you think about it, you dont usually wake up in the middle of the night to poop, says Patricia Raymond, MD, a board-certified doctor in both gastroenterology and internal medicine. If you ingest a probiotic at night when your bowel isnt moving, theres a better chance that it will hang around, divide, and potentially get integrated into your gut.

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Why You Should Eat Probiotic Food On An Empty Stomach

For the beneficial bacteria in probiotic foods to make it to your large intestinethe gut of your gut microbiomeit must first pass through your harsh stomach acids. Your stomach is designed to break down food, drink, and any other particles. Unfortunately, that includes probiotics.

When you eat, the production of gastric acid in your stomach is increased to aid the digestion process. But while this acid is crucial for digestion, it can be greatly detrimental to probiotic foods. In fact, when eaten at the wrong time, a whopping 60% of the beneficial bacteria could be killed by gastric acids!

You want to give the beneficial bacteria in your food the chance to make it through that hostile acidic environment relatively unscathed. That means consuming probiotic-friendly food when your stomach isnt in digestion mode, to minimize the amount of gastric acid that might attack the probiotics.

Billion Cfu Probiotic Supplement By Toniiq

The Toniiq probiotic is special due to its Multi-Layer Micro-Encapsulation Preparation. As discussed in further detail below, digestibility is critical because, without it, you wont get the full benefit from your probiotic. This probiotic powder is truly digestion-viable as its freeze-dried and coated with a core layer of biofilm. This promotes steady-state and targeted controlled release of probiotic cells, as well as an outer wall for protection against acids, salts, and temperature damage.


Ora is a reputable brand known for its highest-quality sourced ingredients. The Organic Prebiotic and Probiotic Powder Supplement is a reliable, shelf-stable probiotic powder excellent for travel and healing IBS symptoms. With its high concentration of bacteria, you will notice its effects quickly.



  • Higher price point than competitors
  • The high concentration of CFUs may be too much for some people those concerned can start with a half dose to see how their body adjusts before increasing the dosage

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Physicians Choice 60 Billion Probiotic With Prebiotic Fiber Blend

With 4.5 stars and 93,265 reviews, the Physicians Choice 60 Billion Probiotic with Prebiotic Fiber Blend is a winner. It contains both prebiotics and probiotics and a very high concentration of CFU. Plus, its shelf-stable, so it doesnt require a fridge! That makes it perfect for traveling.


  • Contains 60 billion CFU, a very high concentration
  • Contains 10 different live strains of helpful bacteria
  • Contains probiotics and prebiotics
  • Free from GMOs, soy, wheat, gluten, milk, eggs, peanuts, shellfish, and preservatives
  • Shelf-stable formula with no refrigeration required
  • Stomach-stable formula with delayed-release acid-resistant capsules
  • Vegan and vegetarian formula
  • Certified B Corporation, meaning it meets rigorous standards of social and environmental performance, transparency, and accountability
  • Tested for 125+ herbicides and pesticides certified glyphosate residue-free, the worlds most common herbicide
  • Small, easy to swallow capsules
  • 4.6 average star reviews on Amazon out of 433 ratings


  • Not shelf-stable: requires refrigeration or freezing, so it is unsuitable for travel

Improvement Of Gut Health And Gut Bacteria Occurs Progressively Not Instantaneously


Even so, research does suggest that the initial benefits of diet-influenced gut health improvements may be noticeable within 3-4 days. Though the main study of interest doesnt specifically look at prebiotic supplementation, a group of researchers did note that the gut microbiome can rapidly respond to altered diet, potentially facilitating the diversity of human dietary lifestyles.

Of course, the initial benefits noticeable within 3-4 days are just the beginning. Compounding over time with daily, consistent use, the benefits of prebiotics include chronic, long-term health advantages from improved gut health and comfort to a healthy immune system and sustained cognitive performance.

Prebiotics supplements and foods work better the longer you use them.

Probiotics vs. Prebiotics: Which is Better?

Probiotics work by introducing new good bacteria to your body, whereas prebiotics nourish the good bacteria already in your body.

In that sense, probiotic supplements, or probiotic-enhanced foods such as kombucha and yogurt, offer supplementary bacteria in whole formsor strains.

Probiotics are good for you however, they can be difficult to process and often tend to denature in the digestive system before implementing their health benefits.

…Not to mention that not all dietary and supplementary probiotics deliver the best strains for your microflora composition.

Also Check: Probiotics For 6 Month Old

Why You Should Take Probiotics With Your Biggest Meal

To answer that question thoroughly, first lets discuss the importance of choosing the right probiotic supplement.

Probiotic supplements are formulated to deliver high quantities of beneficial bacteria to your gut while working with your bodys normal functions, including the gastric acids in the digestive system.

In that sense, probiotic supplements can be a life jacket for your beneficial bacteria.

It is important to note that the number of CFUs in a probiotic isnt that important. This is a point of confusion for many people, due to misinformation and misconceptions . Survivability, on the other hand, is critical, and if your probiotics are not taken at the right time and not formulated for survivability, it doesnt matter how many probiotics are in your supplement.

Like any nutritional supplement, probiotics from different sources can vary greatly in effectiveness. Survivability studies with some of the leading probiotics indicate that 99% of the strains cannot survive digestion. This shocking finding suggests that most people are paying for products with less than 1% survivability. When it comes to optimizing your levels of beneficial bacteria, its crucial to choose the highest quality option: spore-based probiotics.

In contrast to other strains of beneficial bacteria, spore-based probiotics thrive during the digestive process, naturally protecting themselves from your stomach acids, and using the food you eat as fuel to better colonize your gut microbiome.

Can I Take Probiotics With My Antibiotics Herbal Supplements Or Prescription Drugs

Well, you can, but its probably not the best time to take probiotics. You see, many herbs and various drugs, especially antibiotics, may damage the probiotics before they make the journey to your intestine. Its better to wait at least two hours after taking herbal supplements or prescription drugs before you supplement with or consume probiotics.

While you may not want to take your probiotics with antibiotics, taking a probiotic while youre using antibiotics has been shown to prevent and relieve antibiotic-induced diarrhea by up to 50%. And higher dosages of probiotics have been shown to be up to two times more effective than lower dosages.

Read Also: Are Probiotics Good For Acid Reflux

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Best Time To Take Probiotics

  • The most important thing is to make sure youre taking the best probiotic strain for your current health concerns or goals!
  • Generally, the best time to take most probiotics is with breakfast, or just after.
  • It’s equally important to take probiotics at a convenient time for you so you dont forget.
  • Different probiotic strains behave differently. Some, such as Saccharomyces boulardii can be taken at any time of day, with or without food.

Check out the following links for further reading

How To Take Probiotics For The Best Health Benefits

When’s the Best Time To Take a Probiotic? – Tip of the Day

Probiotics are a popular topic among health enthusiasts and medical professionals, alike, and rightfully so! As individuals seek to improve their health by becoming advocates for themselves, probiotics are often a good choice to become part of their new health-focused regimen.

However, there are some ways that will allow you to maximize the health benefits that you can get from probiotics. Read on to learn more about how to take probiotics for the best health benefits.

Also Check: Garden Of Life 40 Billion Probiotic

It Depends On Your Stomachs Sensitivity

Healthy people dont typically experience side effects from probiotics. However, at first you might experience minor levels of digestive discomfort. Rest assured that any symptoms should improve as your body gets used to the new probiotic.

In this case, the best time of day to take probiotics can be at night before bed. This timeframe can reduce some of those symptoms you may experience during the day.

Choose The Right One For Your Health Condition

If you have a particular health condition, you may want to consider a specific strain of probiotic or consult a medical professional to find one thats best for you.

Experts agree that Lactobacillus and Bifidobacterium strains benefit most people .

In particular, Lactobacillus rhamnosus GG and Saccharomyces boulardii may reduce your risk of antibiotic-related diarrhea, while E. coli Nissle 1917 may help treat ulcerative colitis (


For a probiotic to work, its live microorganisms must reach your large intestine and colonize it. Look for a supplement that guarantees at least 1 billion live cultures on the label and ask your healthcare provider whether a particular strain is best for you.

Also Check: Does Probiotic Yogurt Help You Poop

What If I Feel Bloated After Taking Probiotics 30 Minutes Before Meals

If your unprotected probiotic causes you to feel gassy and bloated when taken before meals, you may want to consider switching to taking it on an empty stomach before bed. Even though you may not get the best results taking it in this manner, it is better than stopping probiotics completely because you feel gassy or bloated.

Now that you know how you should take your probiotic you should verify what kind of probiotic you have protected or unprotected and take them accordingly. If you’re interested in the technical details on how the study was done, read on.

The Research Behind The Best Time to Take Probiotics

The study on optimal probiotic dosing used a pretty ingenious model of the human digestive system to get these measurements. The study found that probiotics are best taken 30 minutes before meals with milk. While the digestive tract model was man-made, the digestive fluids used were genuine, including saliva, acids, bile, and enzymes.

Researchers used a commercial probiotic supplement containing Lactobacillus helveticus, Lactobacillus rhamnosus, Bifidobacterium longum, and Saccharomyces boulardii to determine the best time to take probiotics. The probiotics were put into capsule form and were put through the in-vitro model along with various food and drink products.

Several types of bacteria are categorized as probiotics, and they each come with their own benefits. The most common types of probiotics include:

The Results

When Is The Best Time To Take A Probiotic

When Is The Best Time To Take Probiotics?

Weve just discussed how probiotics work by rebalancing the gut microbiome to be more in favor of healthy gut bacteria.

This is a gradual process. You cannot completely change the composition of your gut microbiome overnight.

While probiotics do have some immediate effects in terms fo promoting the proper digestion of food , the real benefits associated with probiotics take several days to really manifest, and potentially 2-3 weeks if you are experiencing ver poor digestive health.

Clearly then, the exact time you choose to take your probiotic is not important.

What matters is that you use your probiotic supplement consistently, taking it at the same time each day. This is how you get the most out of probiotics to completely change the gut microbiome, you must ensure there is healthy amount of beneficial, gut-friendly bacteria in the gut 24/7 for a good few days or weeks.

Another thing to consider is the fact that probiotics tend to have the most effect when consumed on an empty stomach.

So the best time of day to take a probiotic is whenever you are most likely to be able to take it at that same time each day and on an empty stomach. For the vast majority of people then, first ting in the morning is a prime candidate you can easily make taking a probiotic part of your morning routine, minimizing your risk of forgetting, and you will have an empty stomach.

In summary: What is the best time of day to take a probiotic?

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