What Has Science Shown About The Effectiveness Of Probiotics For Health Conditions
A great deal of research has been done on probiotics, but much remains to be learned about whether theyâre helpful and safe for various health conditions.
Probiotics have shown promise for a variety of health purposes, including prevention of antibiotic-associated diarrhea , prevention of necrotizing enterocolitis and in premature infants, treatment of infant colic, treatment of periodontal disease, and induction or maintenance of remission in ulcerative colitis.
However, in most instances, we still donât know which probiotics are helpful and which are not. We also donât know how much of the probiotic people would have to take or who would be most likely to benefit. Even for the conditions that have been studied the most, researchers are still working toward finding the answers to these questions.
The following sections summarize the research on probiotics for some of the conditions for which theyâve been studied.
Probiotics Can Help Prevent And Treat Diarrhea
Probiotics are widely known for their ability to prevent diarrhea or reduce its severity.
Diarrhea is a common side effect of taking antibiotics. It occurs because antibiotics can negatively affect the balance of good and bad bacteria in the gut (
A review of 15 human studies found supplementing with Bifidobacterium and Lactobacillus strains for 12 months can improve anxiety, depression, autism, obsessive-compulsive disorder and memory .
One study followed 70 chemical workers for 6 weeks. Those who consumed 100 grams of probiotic yogurt per day or took a daily probiotic capsule experienced benefits for general health, depression, anxiety and stress .
Benefits were also seen in a study of 40 patients with depression.
Taking probiotic supplements for 8 weeks decreased depression levels and reduced levels of C-reactive protein and hormones such as insulin, compared to people who did not take a probiotic .
Research shows taking probiotics may help improve symptoms of mental health disorders such as depression, anxiety, stress and memory, among others.
Where To Find Digestive Enzymes
As far as digestive enzymes go, you can find some foods that contain them. For example, pineapple contains a group of proteases called bromelain, while bananas contain amylases and glucosidases that break down starches. Other food-based digestive enzymes include:
- Papaya, which contains the proteases papain that break down protein
- Mangoes, which contain amylases that break down starch
- Raw honey, which contains diastases and amylases that break down starches, invertases that break down sucrose, and proteases that break down protein
- Avocados, which contain lipases that break down fats into smaller molecules that the body can absorb
- Kefir, which contains lipase, proteases, and lactase
- Ginger, which contains the protease zingibain
- Kiwifruit, which contains the protease actinidain
Fermented foods like kimchi, sauerkraut, and miso also contain a variety of digestive enzymes. But keeping track of the foods you eat every day and making sure you consume enough enzymes from each can be time-consuming. So, if you want multiple digestive enzymes in a simple daily dose, then choose a supplement like Smarter Nutritions Smarter Enzymes.
Probiotics And Side Effects
If you are a healthy person, you likely won’t have many, if any, negative side effects from taking probiotics. The only adverse effect you might experience is gas, which is a sign that you’re taking too much. For people with certain health complications taking probiotics can lead to more severe complications. So, as always, talk to your doctor before you start taking these supplements.
Of particular concern are those with compromised immune systems. An April 2019 article published by the Parker Institute for Cancer Immunotherapy indicates that cancer patients taking probiotics have poorer immune systems and recovery rates.
The National Center for Complimentary and Alternative Medicine also noted the poor reactions between probiotics and immunosuppressant medications. Overall, this further provides evidence that you need to confirm with your doctor that taking probiotics will benefit you.
There still needs to be additional research on the safety of probiotics. Unfortunately, the focuses of most studies have been their impact on different ailments. While these benefits are essential to prove or disprove, there hasn’t been enough investigation into possible adverse reactions.
Probiotics May Reduce The Severity Of Certain Allergies And Eczema
Certain probiotic strains may reduce the severity of eczema in children and infants.
One study found eczema symptoms improved for infants fed probiotic-supplemented milk, compared to infants fed milk without probiotics .
Another study followed children of women who took probiotics during pregnancy. Those children had an 83% lower risk of developing eczema in the first two years of life .
However, the link between probiotics and reduced eczema severity is still weak and more research needs to be done .
Some probiotics may also reduce inflammatory responses in people with milk or dairy allergies. However, the evidence is weak and further studies are needed .
Probiotics may reduce the risk and severity of certain allergies, such as eczema in infants. However, more research is needed.
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How Is This Medicine Best Taken
Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take with or without food. Take with food if it causes an upset stomach.
- Swallow whole. Do not chew or crush.
- Some products may be opened and sprinkled on a spoonful of applesauce. Some products must be swallowed whole. Check with your pharmacist to see if you can open this product.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What Are Some Side Effects That I Need To Call My Doctor About Right Away
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash hives itching red, swollen, blistered, or peeling skin with or without fever wheezing tightness in the chest or throat trouble breathing, swallowing, or talking unusual hoarseness or swelling of the mouth, face, lips, tongue, or throat.
- Change in how much urine is passed.
- Muscle pain.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
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Probiotics May Help Boost Your Immune System
Probiotics may help give your immune system a boost and inhibit the growth of harmful gut bacteria .
Also, some probiotics have been shown to promote the production of natural antibodies in the body. They may also boost immune cells like the IgA-producing cells, T lymphocytes and natural killer cells (
Certain probiotics may help you lose weight and belly fat. However, other strains have been linked to weight gain.
Will Digestive Enzymes Help With Bloating
Digestive Enzymehelp with bloatingenzymescan helpenzyme
- Best Overall: Zenwise Health Digestive Enzymes Plus Prebiotics and Probiotics.
- Best for IBS: Garden of Life Vegetarian Digestive Supplement.
- Best for Gas: MAV Nutrition Digestive Enzymes Premium Digestive Support.
- Best for Gluten: Healthy Digestives Gluten Cutter Enzyme Formula.
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Who Should Use Nucific Probiotic Complex*
One of the best things about Nucific Probiotic Complex is that everyone can benefit from the power of probiotics. Whether you want help to lose weight, improve your digestion, or just have better energy and focus, Probiotic Complex can make a difference.
Given the prevalence of added sugars and artificial sweeteners and unnatural additives in the American diet, Nucific Probiotic Complex can help anyone digest more efficiently and get more from the food they eat.
What Do Probiotics Do In Your Body
To understand how probiotics work, you first need to know about something called your microbiota.
Your microbiota is the name researchers give to the trillions of microorganisms that live in and on your body and function together with you in a perfect balance or in imbalance .
When you consume healthy bacteria that are normal, healthy residents of your microbiota, they set up camp. They attach themselves to your villi the tiny hairs lining your intestines multiply, build colonies, and boost the overall health of your microbiota.
This allows your microbiota to carry out the normal activities it uses to help keep you healthy even better. The most important of these activities include:
- Removing dangerous bacteria from your digestive tract
- Producing chemicals that kill infectious bacteria
- Strengthening your intestinal wall
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What Are Digestive Enzymes With Probiotics
This vegetarian-friendly digestive health formula is good for anyone trying to up their intake of hard-to-digest veggies, legumes, fruit, or leafy greens. It contains a scientifically formulated blend of digestive enzymes, as well as a beneficial probiotic strain to help maintain healthy GI balance.
Issues To Be Aware Of
If you’re considering trying probiotics, there are a few issues you need to be aware of.
Probiotics are generally classed as food rather than medicine, which means they don’t go through the rigorous testing medicines do.
Because of the way probiotics are regulated, we can’t always be sure that:
- the product actually contains the bacteria stated on the food label
- the product contains enough bacteria to have an effect
- the bacteria are able to survive long enough to reach your gut
There are many different types of probiotics that may have different effects on the body, and little is known about which types are best.
You may find a particular type of probiotic helps with one problem. But this doesn’t mean it’ll help other problems, or that other types of probiotic will work just as well.
And there’s likely to be a huge difference between the pharmaceutical-grade probiotics that show promise in clinical trials and the yoghurts and supplements sold in shops.
Page last reviewed: 27 November 2018 Next review due: 27 November 2021
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Assessment Of Publication Bias
The publication bias is assessed using funnel plots and further regression tests for funnel plot asymmetry is done in every case . Using Eggers mixed effects meta regression model, the publication bias is predicted based on the standard error and rank correlation test for asymmetry, using Kendells Tau statistics for ADFI, ADG, CP, GE, G:F, and La:Ec . Eggers test for fatty acids and La:Ec showed no significance, which indicates that there is no evidence for publication bias in this case. However, although the ADFI and G:F results are non-significant, they are comparatively lower than the former ones. Although, there is no consensus for the beneficiary effects of ADFI, ADG, GE, CP, or G:F in feed supplemented with enzymes, in the case of La:Ec and FA, the effects of enzyme supplementation are observed in some studies,,.
Funnel plots to assess the publication bias. ADFI. ADG. CP. GE. GF. La:Ec. Fatty acids. ADFI: Average daily feed intake ADG: Average daily gain LB: Lactobacillus Ec: Escherichia coli V/VH: Villus height, C: Crypt depth, CP: Crude protein GE: Gross energy GF: Gain to Feed ratio, and La:Ec: Lactobacillus : E. coli La:Ec ratio.
They May Cause Unpleasant Digestive Symptoms
It is not known exactly why some people experience these side effects, but they typically subside after a few weeks of continued use .
To reduce the likelihood of side effects, start with a low dose of probiotics and slowly increase to the full dosage over a few weeks. This can help your body adjust to them.
If the gas, bloating or any other side effects continue for more than a few weeks, stop taking the probiotic and consult a medical professional.
Some people experience an increase in gas, bloating, constipation or thirst when they start taking probiotics. These side effects should go away within a few weeks.
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Do I Need To Take Probiotics After I Take Antibiotics
Antibiotic medications are often needed to fight an infection. However, while antibiotics are killing the bad bacteria, they are also knocking out the good bacteria in your body. Some people develop conditions like diarrhea after taking an antibiotic. In other people, this may allow for really bad bacteria to take over and populate the gut, such as with C. diff. Some research has shown a positive connection between taking probiotics after an antibiotic and relief from diarrhea. This hasnt been proven yet and doesnt work for everyone.
The thought behind adding probiotics back into your body after taking an antibiotic is that it can repopulate the good bacteria that was destroyed by the antibiotics and re-boot your system. The extra good bacteria helps repopulate your gut and fight off any remaining bad bacteria. Many people feel that adding in probiotics wont hurt, might help you feel better a little faster and prevent diarrhea.
Some Ingredients May Cause Adverse Reactions
People with allergies or intolerances should read the labels of probiotic supplements carefully, since they might contain ingredients they could react to.
For example, some of the supplements contain allergens such as dairy, egg or soy.
These ingredients should be avoided by anyone who is allergic, as they may trigger an allergic reaction. If necessary, read labels carefully to avoid these ingredients .
Similarly, yeast-based probiotics should not be taken by those with yeast allergies. Instead, a bacteria-based probiotic should be used .
Milk sugar, or lactose, is also used in many probiotic supplements .
While studies suggest that most people with lactose intolerance can tolerate up to 400 mg of lactose in medications or supplements, there have been case reports of adverse effects from probiotics (
Some people experience gas and bloating when consuming synbiotics. Those who experience these side effects may want to select a supplement that does not contain prebiotics .
Probiotic supplements can contain allergens, lactose or prebiotic fibers that may cause adverse reactions in some people. These ingredients can be avoided by reading labels.
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Can I Use Probiotics To Help With Medical Conditions
There is currently a large amount of research happening around the idea of what probiotics can do for your body. Even though there are a lot of possibly positive outcomes, researchers are still working to find definitive answers about how probiotics can help with various conditions.
However, there are some medical conditions where probiotics may help. This can vary between people meaning that what works for one person may not work for another. These can also vary based on the certain probiotic that is taken.
Some of the conditions that might be helped by increasing the amount of probiotics in your body include:
- Upper respiratory infections .
Neo Probiotic Complex 15 Capsules
Neo Probiotic Complex 15 capsules description Probiotic Complex neo ® is a probiotic supplement that helps maintain and restore intestinal wellbeing. Probiotics are a good alternative, natural and without side effects, to improve bowel function…
Neo Probiotic Complex 15 capsules description Probiotic Complex neo ® is a probiotic supplement that helps maintain and restore intestinal wellbeing. Probiotics are a good alternative, natural and without side effects, to improve bowel function and, by extension, improve our health, usually affected by stress, poor eating habits and drug abuse. Composition per capsule Megaflora 9 ® 250 mg FOS 75 mg How to use Take 1 capsule daily with a glass of water. Precautions May contain traces of soy and milk. Not suitable for people with allergies. observations Food supplements should not be used as a substitute for a balanced diet. Do not exceed the recommended daily dose. Keep container in a cool, dry place out of reach of children.
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What Does A Probiotic Complex Supplement Contain
There are two main categories of good bacteria used in probiotic supplements: lactic acid bacteria and bifidobacteria.
A probiotic complex supplement might contain a few different types of bacteria within those categories. It might also contain some other types of bacteria, such as streptococcus thermophilus.
Along with live bacteria, probiotic supplements might contain some essential nutrients, like B vitamins, or some additional ingredients said to be beneficial for gut health.
How Do Probiotics Work
The main job of probiotics, or good bacteria, is to maintain a healthy balance in your body. Think of it as keeping your body in neutral. When you are sick, bad bacteria enters your body and increases in number. This knocks your body out of balance. Good bacteria works to fight off the bad bacteria and restore the balance within your body, making you feel better.
Good bacteria keeps you healthy by supporting your immune function and controlling inflammation. Certain types of good bacteria can also:
- Help your body digest food.
- Keep bad bacteria from getting out of control and making you sick.
- Create vitamins.
- Help support the cells that line your gut to prevent bad bacteria that you may have consumed from entering your blood.
- Breakdown and absorb medications.
This balancing act is naturally happening in your body all of the time. You dont actually need to take probiotic supplements to make it happen. Good bacteria is just a natural part of your body. Eating a well-balanced diet rich in fiber every day helps to keep the number of good bacteria at proper levels.
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