Wednesday, September 28, 2022

Bacillus Subtilis Probiotic Side Effects

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Is Bacillus Subtilis Dangerous? Primal Defense, a Review
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+ Promising Potential Benefits Of The Probiotic B Subtilis

Biljana Novkovic, PhDJonathan Ritter, PharmD, PhD Puya Yazdi, MDBiljana Novkovic, PhD

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Is Biofit A Safe Solution For Individuals Who Are Facing Weight Issues

BioFit can be used by any adult safely because it offers only natural and safe ingredients. It undergoes testing to ensure that every product is high in quality and purity. However, individuals with a medical condition or currently have a weight loss regimen set up with their doctor should consult a professional first.

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Excessive Immune Stimulation In Susceptible Individuals

Because probiotics have been shown to affect both the innate and adaptive immune systems, including effects on cytokine secretion and dendritic cell function , concern has been raised about the potential to overly stimulate the immune response in some individuals, possibly leading to autoimmune phenomena or inflammation. This theoretical concern has not been reported in any human subjects.

Bacillus Subtilis: Soil Organism Or Probiotic Or Both

(PDF) Effects of Probiotic (Bacillus subtilis DE111 ...

Bacillus subtilis means thin and rod-shaped and it was first discovered in the 1870s. It is one of the best-characterized species of all the Gram-positive bacteria. Like other Bacillusspecies, it forms endospores when conditions are not favorable. It is able to grow well in oxygenated environments but can adapt to low-to-no oxygen. It is able to propel itself with flagella, whip-like appendages, found around its body.

Bacillus subtilis, or B. subtilis, is a ubiquitous naturally occurring Gram-positive bacterium that is commonly recovered from soil, water, air, and decomposing plant material. It also is one of those microbes in which the strain used is extremely important for several reasons:

  • Studies show that there is a high genetic variety in B. subtilis even in strains harvested from the same source.
  • Some strains are capable of producing toxins.
  • Some products have listed B. subtilis on their labels when in fact they were another Bacillus species known to produce toxins such as Bacillus cereus. This is because the B. subtilis classification has undergone changes over the years.
  • Bacillus subtilis, in general, stimulates the immune system, but this effect has to be determined on a microbe-by-microbe basis. While this may be beneficial for intestinal immune-system development, it may not be a desired characteristic universally.

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Additional Bacillus Subtilis Benefits

Bacillus subtilis benefits extend beyond the gut, and may have a positive effect on our immune function. Supplementing with B. subtilis can even reduce the number of sick days that we need to take during the winter months .

One study also showed the pain relieving-effect of Bacillus subtilis in patients. It effectively reduced the symptoms of neck and shoulder tension and considerably improved headache scores . It is important to note that, while the effects were significant among the participants, the results did not stand out when compared to placebo.

Additionally, we can see that Bacillus subtilis benefits include reducing cholesterol levels and improving blood vessel tone .

Along with its ability to increase beneficial bile-acids that have lipid-lowering effects, these findings indicate that B. subtilis may have a unique protective effect against cardiovascular disease . However, more clinical research is needed to explore all of the potential heart-healthy effects of B. subtilis.

What Is B Subtilis Used For

Bacillus subtilis strains, many of them genetically-engineered, are used in various applications. Some of these are:

  • As a bacteriocide and fungicide sprayed on plants or seeds or mixed in the soil
  • As an important source of industrial enzymes and polymers
  • In the production of natto, a traditional Japanese dish of fermented soy beans
  • In the production of medically important enzymes such as nattokinase or Douchi fibrinolytic enzyme used to reduce blood clotting
  • In animal feed, predominantly as a fattening agent
  • As part of a genetically modified corn, Maize MON 87460, to increase the corns drought resistance
  • As a probiotic

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Bacillus Coagulans Bacillus Subtilis Effective In Functional Dyspepsia Treatment

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Spore-forming probiotics were safe and effective in the treatment of patients with functional dyspepsia, according to research published in the Lancet Gastroenterology and Hepatology.

First-line therapy for functional dyspepsia is acid suppression with . … Previous studies suggested efficacy of probiotics for PPI-related side effects and uninvestigated dyspeptic symptoms, which could be caused by an altered small intestinal microbiome,Lucas Wauters, MD, University Hospitals Leuven, and colleagues wrote. Despite beneficial effects of Bacillus coagulans and Bacillus subtilis strains on gut permeability and inflammation in in vitro models, clinical trials on the effect of spore-forming probiotics are absent in human disorders with similar alterations, including functional dyspepsia.

According to study results, the proportion of clinical responders was higher for probiotics vs. placebo . Further, response with probiotics was not significantly higher when comparing PPI use with no PPI use . Researchers noted a similar number of patients experienced adverse events among both groups .

B Coagulans Supplement For Men

Effects of Bacillus and Lactobacillus species in milk replacer

Digest Strong Probiotic Man Blend contains large doses of B. Coagulans.

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B Subtilis Boosts Immunity

B. subtilis spores stimulate the immune response when co-administered with a vaccine for papillomavirus type 16 in mice .

B. subtilis both can instruct a balanced Th1 and Th2 immune response to specific antigens in mice .

Intravenous injection of B. subtilis in mice induces plasma IFN-y production .

B Subtilis Is Beneficial In Ibd

In Asian studies involving patients with ulcerative colitis, the addition of a B. subtilis probiotic significantly reduced the number of days with bloody stool, lead to complete remission without relapse, and significantly increased the efficacy of mesalazine or sulfasalazine therapy .

A higher dose of B. subtilisis administration ameliorated dysbiosis and gut inflammation by balancing beneficial and harmful bacteria and associated anti- and pro-inflammatory cytokines in mice ).

B. subtilis and its competence and sporulation factor ameliorate intestinal inflammation and improve survival in mice with colitis .

B. subtilis reduces inflammation and suppresses colitis in rats .

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What Is The Most Important Information I Should Know About Probiotic Formula

Before using bacillus coagulans and inulin, talk to your healthcare provider. You may not be able to use this product if you have certain medical conditions.

Avoid using this product if you are pregnant. Tell your doctor if you become pregnant.

Avoid using this product if you are breastfeeding.

Do not give any herbal/health supplement to a child without medical advice.

Immunomodulatory Properties Are Strain Specific

(PDF) Effects of probiotic supplement (Bacillus subtilis ...

Figure 3. Effect of apical application for 16 h of different B. subtilis strains on IL-8 release of Caco-2 cells with or without subsequent 6 h basolateral stimulation with IL-1 or flagellin , or apical stimulation with DON . EGCG was used as positive control. Labeled means without a common letter differ within each condition, p< 0.05.

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B Subtilis Probiotic Why Is It Useful

B subtilis probiotic has saved countless burn victims lives. Since the 1950s it formed the basis of the topical antibiotic Bacitracin a treatments for cuts and burns.A.

Newer reserach has shown B subtili probiotic is also effective in the treatment of gastrointestinal and urinary tract disorders.

Are There Any Other Charges Associated With Biofit

No. Users are only charged the single time that their transaction takes place. They will not see another charge until they order their next package.

Consumers with other questions or the desire to return their product can reach out to the customer service team by calling 1-800-266-0373 or sending an email to .

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Types Of Spore Probiotics

Spore probiotics are generally of the Bacillus genus and are limited to those having shown benefits in clinical settings. The following are common species found in spore-based probiotics:

  • Bacillus indicus
  • Bacillus lichenformis
  • Bacillus megaterium

Note: The numbers in parenthesis after the spore names are specific strains. These are useful in assuring that your products contain the same bacteria that were actually tested in clinical settings.

Frequently Asked Questions About Biofit

Probiotics SBOs Bacillus Subtilis

The historic rise in recognition surrounding the BioFit probiotic weight loss pills has been nothing short of amazing and incredible to witness. However, when things are moving so fast and there is a lot of new information to consume, there are many questions that remain at-large that need a proper deep-dive session in order to fully comprehend and understand so each consumer has complete confidence in their .

Here are the most popular questions about using BioFit probiotic and the best researched answers with all of the available information to-date:

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Is Bacillus Subtilis Safe

B. subtilis is thought to have a weak ability to cause disease in humans unless the number of bacteria a person consumes is very high or the immune status of the person is very low. Concerns about Bacillus probiotics in general are covered here.

NOTE: Probably due to the possibility of any virulence, NO Bacillus subtilis strain has GRAS status as of March, 2015 in the US. Some sites claim theirs does, but do not believe it as it is NOT true. Some enzymes produced from B. subtilis have GRAS status, but the bacterium itself does not. B. subtilis has been granted QPS status by EFSA for certain applications in animal feeds and for vitamin K2 production for foods and supplements consumed by humans.

Some strains are used as controlled pharmaceutical agents in Asia and are accepted in the Ukraine, Russia and Italy in products such as Biosporin, Lactipan Plus and Medilac-Vita. Other products labeled as containing B. subtilis may in fact have other species.

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B Subtilis Beneficially Modifies Gut Microbiota

Ingestion of significant quantities of B. subtilis spores is thought to restore the normal gut microbiota in humans following extensive antibiotic usage or illness .

B. subtilis increases Bifidobacteria, decreases some Clostridium groups , and enhances the growth of L. reuteri and L. acidophilus in laboratory experiments .

Effects Of Bacillus Subtilis Dietary Supplementation On Intestinal Microbiota And Metabolites In Weaned Piglets

Effect of the probiotic Bacillus subtilis on the growth ...

Beneficial impact on weaned piglets intestinal microbiota after B. subtilis supplementation by the diversity, composition, and metabolites of intestinal microbiota.

In the swine industry, early weaning can improve sow reproductive performance and farrowing room utilization. However, early weaned piglets tend to have impaired gut morphological structure and function disorders. Traditionally, dietary antibiotics supplementation has been considered as an efficient strategy to solve this problem, but there is a tendency to decrease its use due to the detrimental effects on gut commensal bacteria and side effects in both human and animal health. Recently, it has been demonstrated that probiotics could be a novel alternative to feed antibiotics. The aim of the present study was to investigate the effects of a probiotic, dietary Bacillus subtilis , on the intestinal microbiota composition and metabolites of weaned pigs. For that purpose, sixty-four piglets were allocated to two groups . Piglets in the control group were fed basal diet and the experiment groups piglets were fed basal diet supplemented with 500 g. At the end of the trial, one pig in each pen was slaughtered to collect the luminal contents in jejunum, ileum and middle colon for microbiota and metabolites analysis. The jejunum and ileum tissues were collected for morphology measurement.

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Probiotic Formula Side Effects

Get emergency medical help if you have signs of an allergic reaction:hives difficult breathing swelling of your face, lips, tongue, or throat.

Although not all side effects are known, Probiotic Formula is thought to be possibly safe when taken by mouth for a short period of time.

  • severe stomach pain

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How Does A Probiotic Supplement Help The Body

Probiotics are a common supplement in the health industry nowadays, offering a wealth of good bacteria to eliminate the bad bacteria built up in the gut. If anyone is unsure if their gut is healthy, there are a few signs that a probiotic should be incorporated. The most obvious sign is the digestive systems irregularity, like irritable bowel syndrome, diarrhea, or constipation. Toxic bacteria may also be flourishing if the individual experiences uncontrollable cravings for sugar and sweets, has a slow metabolism, is taking medication, or notices differences in their complexion.

When the user takes any probiotic supplements , users can eliminate any of the risk factors it has caused. As those bad bacteria leave the body, the user will notice a change in their symptoms. The desire to consume high amounts of sugar will go down, and they wont have the same digestive issues in the bathroom anymore. The changes in their complexion should also be obvious within a few weeks of starting a probiotic regimen.

Studies regarding the impact that probiotics can make on weight loss seem that Lactobacillus rhamnosus is the most effective strain to eliminate extra weight. One recent study showed that women who took probiotics for their diet could lose up to 50% more weight over three months.

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What To Look For

B. coagulans is sold as a stand-alone supplement or in combination with other probiotics. If purchasing a broad-spectrum probiotic, read the label to ensure it contains B. coagulans.

Dietary supplements are not regulated by the U.S. Food & Drug Administration . To make sure you are buying a quality probiotic, look for a trusted, independent third-party seal on the label, such as U.S. Pharmacopeia, NSF International, and ConsumerLab. This does not guarantee safety or efficacy, but it can reassure you that what’s advertised on the label is what you’re getting.

Researched Benefits Of B Coagulans Supplements

Bacillus subtilis Probiotic Bacteria is Safe and Friendly

Bacillus Coagulans is a powerful probiotic strain that is therapeutically prescribed to patients needing acute immune support in Israel, France & Germany.

Research and clinical practice has shown strong evidence for B. coagulanss ability to fight off invading viruses & pathogens. Bacillus coagulans typically lives in the digestive tract and has also been shown to decrease IBS abdominal pain and bloating symptoms.

This probiotic is extremely hardy and can easily survive stomach acid to colonize the entire GI tract. B. coagulans is closely related to other soil-based-organism probiotics. This probiotic was first discovered around 1930.

Interestingly, this probiotic was used in WWII to treat people with digestive issues such as dysentery.

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