Probiotics With Lactobacillus Acidophilus And Bifidobacterium

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Garden Of Life Dr Formulated Probiotics Once Daily 30 Billion Cfus

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Garden of Life Dr. Formulated Probiotics Once Daily 30 Billion CFUs provides 30 billion CFUs of 14 probiotic strains, including Bifidobacterium lactis, Lactobacillus acidophilus, and Lactobacillus casei.

Garden of Life guarantees the CFU count through the end of the products best use date when stored properly. This supplement keeps best in the refrigerator.

This product is dairy-free and makes a good choice for those with lactose intolerance.

While its also made without peanuts, tree nuts, shellfish, and soy products, the supplement is manufactured in a facility that handles major allergens, so it may not be a good option if you have a severe food allergy.

It May Help Prevent And Reduce Symptoms Of Eczema

Eczema is a condition in which the skin becomes inflamed, resulting in itchiness and pain. The most common form is called atopic dermatitis.

Evidence suggests that probiotics can reduce the symptoms of this inflammatory condition in both adults and children .

One study found that giving a mix of L. acidophilus and other probiotics to pregnant women and their infants during the first three months of life reduced the prevalence of eczema by 22% by the time the infants reached one year of age .

A similar study found that L. acidophilus, in combination with traditional medical therapy, significantly improved atopic dermatitis symptoms in children .

However, not all studies have shown positive effects. A large study in 231 newborn children given L. acidophilus for the first six months of life found no beneficial effect in cases of atopic dermatosis . In fact, it increased sensitivity to allergens.

Summary:

Some studies have shown that L. acidophilus probiotics can help reduce the prevalence and symptoms of eczema, while other studies show no benefit.

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Analysis Of Nec Risk Factors

Infants developing NEC were more immature vs. no NEC: 28+0 P = 0.005) than infants without NEC . Premature rupture of membranes as cause for preterm birth was observed more often in infants with NEC , and these infants also received prenatal antibiotics more frequently . All other basic clinical and demographic data did not differ significantly . Infants with NEC received significantly less breast milk during their first 2wk of life but a comparable amount of formula .

Lactobacillus And Bifidobacterium In The Immune System

As an immunologist, my focus has been on how the immune system works and what happens when something goes awry. It wasnt until recently that I began to look at how the microbiome affected the outcomes of our experiments and how probiotics could be used to help treat patients with cancer or autoimmune disease.

Several studies have also shown benefits for combining Bifidobacterium and Lactobacillus when treating inflammatory bowel diseases. One uncontrolled study showed that B. bifidum Bb12 given with Lactobacillus acidophilus over three weeks doubled the number of peripheral white blood cells with that could engulf and destroy pathogens.1314

Additionally, benefits for patients with the autoimmune disease Crohns or Ulcerative Colitis were reported in a double-blind, placebo-controlled trial, with a combination of eight probiotics, including B. longum, B. breve, and B. infantis prevented relapse of chronic pouchitis after remission.1516 UC patients also seemed to have better symptom control when given a supplement with a mixture of Lactobacilli La-5 and Bifidobacterium Bb-12 as well as fermented milk with live B. breve, B. bifidum and L. acidophilus YIT 0168.171819

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Effects Of Probiotics On Il

A shown in , all probiotics-treated inflammatory HT-29 cells had significantly lower IL-8 levels than did cells stimulated with LPS and TNF-α . In addition, the IL-8 level was significantly lower in group AB than in either group A or B.

Effects of probiotics on IL-8 secretion in inflammatory HT-29 cells. All values except for control are mean ± SD . Bars with the same letter are not significantly different from one another determined by Duncanâs multiple range test, p< 0.05. C, control I, TNF-α with lipopolysaccharide A, L. acidophilus at MOI of 1 with TNF-α and LPS B, B. animalis subsp. lactis at MOI of 10 with TNF-α and LPS AB, L. acidophilus at MOI of 1 and B. animalis subsp. lactis at MOI of 10 with TNF-α and LPS .

For Ibs And Other Functional Gastrointestinal Disorders: Bifidobacteria Maybe

A functional gastrointestinal disorder is a problem where theres no obvious physical cause of symptoms, but the symptoms are still there. Youre not constipated or bloated or having diarrhea because you have a virus or parasite theres nothing physically wrong with your digestive systembut the problem wont go away!

A recent review and meta-analysis looked at all the data for probiotics in IBS and chronic idiopathic constipation . The researchers found:

• Theres evidence that probiotics as a group are helpful.
• Theres some evidence that bifidobacteria may be particularly helpful.
• We need more high-powered studies to really learn about the differences between the types of probiotics.

Bifidobacteria include anything labeled as B. _______ . If youre trying to manage IBS or constipation, look for that on the probiotic bottle.

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Trc Khi Dng Li Khun Lactobacillus Acidophilus Bn Nn Bit Nhng G

i vi nhng trng hp mc bnh không dung np ng lactose, không nên dùng li khun di dng các thc phm t sa mà nên dùng các loi thuc nén.

Bn có th hi bác s v vic kt hp L. acidophilus vào ch dinh dng ca bn chng nhim trùng cng nh tng cng h min dch.

Dù có nguy c mc phi nhim trùng nm khi s dng L. acidophilus và thuc kháng sinh, bn nên dùng các loi thuc kháng sinh mà bác s yêu cu. L. acidophilus có th c s dng mà không làm nh hng n các ch ung thuc, n ung hay luyn tp ca bn.

Nhng quy nh cho li khun L. acidophilus ít nghiêm ngt hn nhng quy nh ca tân dc. Cn nghiên cu sâu hn xác nh an toàn ca v thuc này. Li ích ca vic s dng li khun L. acidophilus nên cân nhc vi nguy c có th xy ra trc khi dùng. Tham kho ý kin t vn ca thy thuc hay bác s trc khi s dng.

Lactobacilli Bifidobacteria Which Probiotic Should I Take

At this point, probiotics are old news. Theyre so well-established that you can walk into any grocery store and take your pick of probiotic novelty foods, some of which are so silly its actually hilarious .

But in all the hype about probiotics, its easy to forget that probiotics is really an umbrella term that includes all types of bacteria with beneficial effects on human health. When a study uses a probiotic to achieve some kind of health improvement, the researchers arent just giving their patients every known probiotic strain of bacteria theyre picking particular species.

Different probiotic species work in various different ways for example, they can crowd out dangerous bacteria by competing with them for food, or they can help modulate the gut immune response, or both, or something else completely. There are hundreds of different strains of beneficial bacteria, and they all have different effects. So is it better to focus on particular kinds? Could some of them actually be harmful? Or should you go for as much diversity as possible without emphasizing one species over another?

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Iv Fecal Microbiology Analysis

DNA was extracted from fecal sample of 30 subjects enrolled in this study . The qPCR assay for L-NCFM demonstrated that genetic sequences associated with this probiotic was detected only in fecal DNA from âpost-probiotic interventionâ samples obtained from subjects on the active arm of the study . The qPCR assay for B-LBi07 demonstrated that genetic sequences associated with these probiotic bacteria was detected in the majority of fecal DNA samples tested in both the active and placebo arms. However, the concentration of these B-LBi07 associated sequences were significantly higher in âpost-probiotic interventionâ samples obtained from subjects on the active arm compared to their corresponding âpre-probiotic interventionâ samples , and âpre-â and âpost-probiotic interventionâ samples obtained from subjects on the placebo arm of the study .

Concentration of Bifidobacterium lactis Bi07 in fecal samples from subjects pre- and post- intervention

Dietary Intervention With The Probiotics Lactobacillus Acidophilus 145 And Bifidobacterium Longum 913 Modulates The Potential Of Human Faecal Water To Induce Damage In Ht29clone19a Cells

Published online by Cambridge University Press: 09 March 2007

Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Haid-und-Neu-Strae 9, 76131 Karlsruhe, Germany

Gerhard Jahreis

Department of Nutritional Physiology, Institute for Nutrition, Friedrich-Schiller University, Dornburger Strae 25, D-07743 Jena, Germany

Gerhard Rechkemmer

Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Haid-und-Neu-Strae 9, 76131 Karlsruhe, Germany

Beatrice L Pool-Zobel*

Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Haid-und-Neu-Strae 9, 76131 Karlsruhe, Germany

*

*Corresponding author: Professor Beatrice L. Pool-Zobel, fax +49 3641 949672

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Iii Safety And Tolerability

The most common adverse events were cold symptoms , fatigue , abdominal pain , sinus infection . There were no differences in these reported adverse events between the intervention and the placebo groups. No significant adverse events or changes in blood tests between baseline to mid- and post-intervention periods were recorded. In addition, analysis of fecal samples for markers of inflammation did not reveal differences between the groups both at baseline and at the end of intervention .

Analysis Of Protein Expression By Western Blot

The analytical procedures were modified from previous studies . Cells were sonicated for 20 min and then lysed cells were centrifuged at 10,000Ãg for 10 min at 4 °C. Supernatants were collected and the protein concentration was determined using the Bio-Rad Bradford assay . Samples were mixed with NuPAGE LDS sample buffer and β-mercaptoethanol , heated at 95 °C for 10 min, cooled to room temperature and electrophoretically resolved on 10% NuPAGE Bis-Tris gels . Proteins were then transferred to polyvinylidene difluoride membrane, which was then blocked with blocking buffer at room temperature for 1 h. The blot was probed with TLR2 , phosphorylated p65 NF-κB , phosphorylated p38 MAPK , cyclooxygenase-2 , intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 polyclonal antibody at 4 °C for 16 h. After being washed extensively to eliminate nonspecific binding, the membrane was incubated with the secondary alkaline phosphatase-labeled antibody at room temperature for 1 h and incubated with 5-bromo-4-chloro-3-indolyl-phosphate/nitroblue tetrazolium substrate solution for 20 min in the dark. The reactive solution was removed, and the reaction was stopped using 50% methanol. Blot intensities were quantified using Bio-Rad Quantity One software . All experimental data are triplicates.

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Effects Of Probiotics On The Expression Of Inflammation

Groups A, B and AB had significantly higher expression of TLR2 and lower expressions of p-p65 NF-κB , p-p38 MAPK and COX-2 than did group I. Group AB showed the best inhibitory effect on the expressions of inflammation-related proteins, including p-p65 NF-κB , p-p38 MAPK and COX-2 . B. animalis subsp. lactis treatment significantly decreased ICAM-1 expression compared with group I, and this inhibitory effect was more potent in group AB than in group B . L. acidophilus alone had no inhibitory effect on ICAM-1 expression but it enhanced the efficacy of B. animalis subsp. lactis when they were used in combination . All probiotics-treated groups had significantly lower VCAM-1 expressions than did group I, while L. acidophilus treatment showed a better inhibitory effect on VCAM-1 than did B. animalis subsp. lactis alone , as shown in F.

B Lactics Probitics Supplementation Benefits

Bifidobacterium Lactis is a very powerful transient probiotic bacteria. Scientific studies have proven that B. Lactis enhances immunity, fights tumor growth, improves digestion and can lower cholesterol.

B. animalis/lactis inhabit the intestines & the colon in great numbers. Generally, their job is to break down body waste & aid in the absorption of various vitamins & minerals

Bifido Lactis is present in raw milk and is used as starter culture for cheese, cottage cheese and butter milk.

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May Improve Symptoms Of Certain Gastrointestinal Diseases

Some of the most well-studied uses of probiotic supplements relate to the treatment of gastrointestinal diseases like irritable bowel syndrome and inflammatory bowel disease .

One review of 11 studies found that 7 of them reported that probiotic supplementation significantly improved symptoms like bloating and abdominal pain in IBS patients, compared with a placebo, while the remaining 4 studies did not find significant improvements.

The review also found that multi-strain probiotics used for at least 8 weeks seemed to be most effective at improving IBS symptoms .

Notably, Lactobacillus acidophilus was present in all of the multi-strain supplement studies that reported significantly improved symptoms .

Multi-strain probiotics may improve some symptoms in those with IBD, though they appear to be less effective for people with Crohns disease.

Evidence is currently limited, and well-designed studies are needed (

34 ).

While some people, including those with IBS and certain types of IBD, may benefit from specific strains of probiotics, in general, most healthy people who follow a nutritious diet and healthy lifestyle do not need to supplement with probiotics.

Plus, some researchers are concerned that the widespread use of probiotics may lead to antibiotic resistance and warn that many studies investigating the safety and efficacy of probiotics are of poor quality .

Its Good For Your Gut Health

Your gut is lined with trillions of bacteria that play an important role in your health.

Generally, lactobacilli are very good for gut health.

They produce lactic acid, which may prevent harmful bacteria from colonizing the intestines. They also ensure the lining of the intestines stays intact (

51 ).

Another study carefully examined the effects of L. acidophilus on the gut. It found that taking it as a probiotic increased the expression of genes in the intestines that are involved in immune response .

These results suggest that L. acidophilus may support a healthy immune system.

A separate study examined how the combination of L. acidophilus and a prebiotic affected human gut health.

It found that the combined supplement increased the amounts of lactobacilli and Bifidobacteria in the intestines, as well as branched-chain fatty acids, which are an important part of a healthy gut .

Summary:

L. acidophilus can support gut health by increasing the amounts of healthy bacteria in the intestines.

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For Mental Health: Nobody Knows

Its becoming increasingly clear that the gut flora can affect areas of the brain involved in mood and emotional health. From increased rates of depression in people with Irritable Bowel Syndrome to studies associating various mental illnesses with gut flora imbalances, an unhealthy gut is bad news for the brain.

Unfortunately, there arent a lot of studies in real live humans to support probiotics specifically:

• This study found that Lactobacillus casei helped with the mental symptoms of chronic fatigue syndrome.
• This study used a combination of L. helveticus and B. longum for hospital anxiety.

There are no systematic reviews of human studies, because there are very few human studies in general.

Probiotics 60 Billion Cfu

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